Centre Jarryd Sage and back row James Benjamin are called into the starting line-up as Dragons face Edinburgh Rugby in the Guinness PRO14 in Scotland on Friday night (kick-off 7.35pm).
Dragons make just two changes for the clash at BT Murrayfield Stadium as the team targets a first away league win of the season.
Benjamin comes in at Number Eight for the encounter, with Ollie Griffiths moving across the back row to play in the seven jersey.
Sage is named at centre alongside Tyler Morgan, as Dragons go into the game with six players away on international duty with Wales.
The only other change to the match day squad is a call-up for Gavin Henson who is named among the replacements.
Backs Coach Barry Maddocks said: “It would be great to get that away win. Edinburgh have strengthened a lot so, even though they will have some players away with Scotland, they are a strong unit.
“We defended well at home when we faced Edinburgh in November and when we had opportunities in attack we took them.
“They will like to play with the ball in hand and like to play for long periods so we will have to be on our mettle.
“It is a fantastic venue and you have got to be excited to play in a stadium like Murrayfield,” he added.
“We know it is going to be a tough game, but the boys are looking forward to it and in good spirits as we return to the challenge of the Guinness PRO14.”
Dragons (v Edinburgh Rugby):
Jordan Williams, Jared Rosser, Tyler Morgan, Jarryd Sage, Will Talbot-Davies, Josh Lewis, Rhodri Williams; Brok Harris, Richard Hibbard (c), Lloyd Fairbrother, Joe Davies, Matthew Screech, Harrison Keddie, Ollie Griffiths, James Benjamin
Replacements: Rhys Lawrence, Rhys Fawcett, Dan Suter, Lewis Evans, Taine Basham, Rhodri Davies, Gavin Henson, Zane Kirchner